Trends in Lumbar Spinal Decompression Surgery at a Single Tertiary Center: A Retrospective Review

Article information

J Minim Invasive Spine Surg Tech. 2026;11(1):65-76
Publication date (electronic) : 2026 April 30
doi : https://doi.org/10.21182/jmisst.2025.03006
1Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
2Division of Spine Surgery, Department of Orthopaedic Surgery, Sengkang General Hospital, Singhealth Health Services, Singapore
3Sofia University St. Kliment Ohridski, Sofia, Bulgaria
4National Neuroscience Institute, Singapore
Corresponding Author: Kai Lin Lee Department of Orthopaedic Surgery, Yong Loo Lin School of Medicine, National University of Singapore, 10 Medical Dr, Singapore 117597 Email: lee.kai.lin@u.nus.edu
Received 2025 November 27; Revised 2026 February 2; Accepted 2026 February 5.

Abstract

Objective

Spinal stenosis and degenerative spinal disorders are increasingly prevalent and have a substantial impact on quality of life. Surgical decompression, performed using either open microscopic or endoscopic approaches, remains a cornerstone of management for these conditions. This study examines evolving trends in single-level lumbar spinal decompression procedures performed at a tertiary academic hospital in Singapore.

Methods

A retrospective observational study was conducted involving 588 patients who underwent single-level spinal decompression between 2021 and 2024, including endoscopic spine surgery (ESS; n=364) and microdecompression (n=224). Primary outcome measures were changes in 36-Item Short Form Health Survey (SF-36) and visual analogue scale (VAS) scores at 3 months, 6 months, and 2 years postoperatively. Secondary outcomes included length of hospital stay, reoperation rates, and operative time. Patient demographics, spinal level and pathology characteristics, surgical techniques, and postoperative outcomes were analyzed. Difference-in-differences (DID) analysis was used to compare outcomes between the 2 groups.

Results

Both groups demonstrated significant postoperative improvements in SF-36 and VAS scores. At 2 years, Short Form Health Survey physical function (SFPF) scores improved in the endoscopic group (mean difference [MD], 18.6; standard deviation [SD], 21.7; p=0.064) and in the open microscopic group (MD, 36.7; SD, 20.9; p=0.007), with a non-significant DID of -18.1 (p=0.155). No DID comparisons across SF-36 domains reached statistical significance. Mean operative time for endoscopic procedures decreased from 249 minutes in 2022 to 145 minutes in 2024, reflecting a procedural learning curve. Surgeons with higher endoscopic caseloads exhibited greater improvements in functional outcomes.

Conclusion

Both endoscopic and open microscopic decompression achieve comparable short- and long-term clinical outcomes. ESS provides similar effectiveness while being associated with shorter recovery periods and reduced hospital stay. Further research is warranted to identify factors contributing to incomplete symptom resolution or the need for revision surgery.

INTRODUCTION

Lumbar spinal stenosis (LSS) is a prevalent and disabling degenerative spinal condition [1-3] affecting almost 103 million people globally [4,5], especially among elderly individuals. It is characterized by the narrowing of the spinal canal and resultant neural compression. Symptoms include back pain, leg pain, neurogenic claudication, or lower limb radiculopathy, significantly impairing mobility and quality of life [6]. The staggering cost burden of low back pain (~$40 billion; ~$2,000/patient/yr) is continuing to rise mainly due to an increasing ageing population [7]. Close to 600,000 surgical procedures are performed in the United States every year to treat LSS [4]. In Singapore, the age-standardized incidence rates per 100,000 population for low back pain were 2371.3 (95% uncertainty Interval, 2056–2714.3), and this number is expected to increase with the ageing population and sedentary lifestyles [8,9].

While conservative treatment such as physiotherapy, analgesia, and epidural steroid injections may alleviate symptoms in some patients, a significant proportion (20–60%) require surgical intervention for symptomatic relief [10,11]. A retrospective cohort study of 531,980 patients found that 1.7% failed nonoperative management and opted for surgery over a 2-year surveillance window [12]. Another retrospective cohort study of 497,822 patients found that 0.8% underwent 1-, 2-, or 3-level posterior lumbar instrumented fusion [13]. Traditional open microscopic decompression surgery, though effective, carries perioperative risks, particularly in older patients or those with multiple comorbidities. Some studies have shown that patients who undergo surgery for spinal decompression for lumbar stenosis have better clinical outcomes [14-18]. A recent meta-analysis by Yang et al. [16] indicated that ESS relieved symptoms, and had a lower incidence of complications and shorter operative time compared to microscopic spinal decompression. Several meta-analyses have compared endoscopic and microscopic decompression for LSS [19-21], but their conclusions should be interpreted cautiously, as many included overlapping patient samples, and all combined data from randomized controlled trials (RCTs) and non-RCTs.

ESS has emerged as a minimally invasive alternative, utilizing specialized cameras and instruments that enable decompression of neural elements through smaller incisions with reduced soft tissue disruption. Endoscopic, compared with open microscopic spinal decompression had a shorter operative time with a mean difference of 2 to 22 minutes [22-25], shorter postoperative stays with a mean difference of 0.17 to 2.30 days [22-26], lower rates of surgical infection [27], and quicker functional recovery [26,28,29]. However, concerns persist regarding its efficacy, learning curve, and long-term outcomes, particularly in comparison to conventional decompression.

This study aims to compare the functional outcomes of ESS versus open microscopic decompression of the lumbar spine, and describe the trends of ESS done at a tertiary institution in Singapore.

METHODS

1. Study Design and Setting

This retrospective cohort study was conducted at a tertiary healthcare institution in Singapore. The study adhered to the STROBE (Strengthening the Report of Observational Studies in Epidemiology) guidelines [30].

2. Study Population

All patients aged 18 years and above who underwent lumbar decompression surgery between January 2021, and December 2024 were included in this study. The inclusion and exclusion criteria are detailed as follows.

1) Inclusion criteria

(1) Patients must present with apparent clinical symptoms, such as lower back pain, leg pain, and intermittent claudication, directly related to the stenosis.

(2) Patients must have either bilateral or unilateral spinal symptoms.

(3) Conservative treatments must have been ineffective, or patients must have experienced recurrent symptoms after at least 6 weeks of treatment.

(4) Patients must have elective single-level spinal decompression surgery.

(5) Follow-up duration must be at least 6 months.

2) Exclusion criteria

(1) Patients with multilevel spinal decompression surgery.

(2) Patients that required emergency surgery.

(3) Patients with spinal trauma.

(4) Patients with spinal infections.

(5) Patients with metastatic spinal disease.

(6) Patients with autoimmune spinal disease.

3. Data Collection

Data were extracted from electronic medical records. Variables included demographics (age, sex, body mass index [BMI], smoking status), comorbidities, magnetic resonance imaging (MRI) findings, surgical details, and functional scores. MRI pathological findings were systematically documented and cross-checked for accuracy. Outcomes were assessed using 36-Item Short Form Survey (SF-36) and visual analogue scale (VAS; back and leg pain) scores at baseline, 3 months, 6 months, and 2 years. Surgical variables included operation time, length of stay, and reoperation rates. Operation time included time for anesthesia and draping, operation time from skin incision to wound closure, and recovery time.

4. Treatment

All patients underwent either endoscopic or open microscopic single-level spinal decompression surgery. All surgeries were performed by 9 board-certified spine surgeons with either interlaminar or transforaminal approach depending on preoperative imaging and stenosis location. The transforaminal approach was primarily utilized for foraminal, or extraforaminal stenosis, with or without concomitant lateral recess stenosis, allowing targeted decompression of the exiting and traversing nerve roots through undercutting of the superior articular process and removal of hypertrophied ligamentum flavum. The interlaminar approach was preferentially used for cases with predominant central canal stenosis to facilitate bilateral or central decompression. In all cases, the extent of decompression was tailored to achieve adequate neural element decompression. Patients were mobilized within 24 hours postoperatively, and standard rehabilitation protocols were followed.

5. Outcome Measures

The primary outcome measures were the SF-36 and VAS scores. Secondary outcomes included length of hospital stay, and reoperation rates.

6. Statistical Analysis

Statistical analyses were performed using RStudio ver. 4.3.3 (R Foundation for Statistical Computing, Austria). Descriptive statistics were used to summarize baseline variables. Continuous variables were expressed as mean±standard deviation or median with interquartile range (IQR). The normality of mean differences in pre and postoperative SF-36 and VAS scores was assessed using the Student t-test, Shapiro-Wilk, Mann-Whitney and Cohen d tests. Statistical significance was set at p<0.05.

7. Ethical Approval

This study was approved by the institutional ethics board (ECOS Ref No. 2020-2381). Consent was waived due to the retrospective nature of the study.

RESULTS

1. Patient Characteristics

A total of 588 cases of single-level lumbar spine decompression cases were done during the study period. 364 cases were endoscopic; 224 cases were open microscopic (Table 1). Median age was 61 (IQR, 45–69) years, with 53.7% male and 46.2% female. Median BMI was 26 (IQR, 23–29) kg/m2, and mean duration of symptoms from diagnosis to surgery for elective cases was 128 days. 93 patients (41.5%) demonstrated more than a single level of pathology on preoperative MRI, but clinical-radiological correlation identified a single symptomatic level responsible for the patients’ predominant symptoms. Consequently, all included patients underwent single-level decompression surgery. Most patients (62.1%) presented with neurogenic claudication, while 37.9% had predominant radicular symptoms. Common comorbidities included hypertension (55.2%), diabetes (28.7%), and obesity (32.2%).

Clinical characteristics, pathology, and surgical characteristics of patients with lumbar spinal stenosis

2. Surgical Characteristics

For single-level unilateral cases, decompression was done via the transforaminal approach in 14.1% of cases, and interlaminar in 85.9%. The mean duration of a single-level ESS was 148 (standard deviation [SD], 75.8) minutes, while that of a single-level open microscopic decompression surgery was 186.0 (SD, 79.4) minutes. The median hospital stay was 1 (range, 1–3) day. No major intraoperative complications were reported. The mean duration of hospital stay was 1.3 (SD, 0.5) days for endoscopic cases, and 1.95 (SD, 2.35) days for microdecompression cases. One revision emergency surgery was required for an endoscopic case, due to inadequate decompression at the original site. One revision surgery was required for a microdecompression case, also due to recurrence of symptoms.

3. Outcomes

A total of 295 patients had documented functional scores at follow-up appointments and 293 patients had no documented follow-up at the point of data collection. Following hospital protocols, these patients would be contacted by telephone on the day of their scheduled appointment and would be given a new appointment within 1 month. For patients who remain unreachable despite repeated efforts, their data were classified as lost to follow-up.

SF-36 and VAS back pain and leg pain scores were used to determine the pre and postoperative functional status up to 6 months. A higher score for SF-36 demonstrates a better patient-reported health status, while a lower VAS score demonstrates lower pain intensity for the patient.

At 1, 3, 6 months, and 2 years postoperatively, both endoscopic and open microscopic groups demonstrated statistically significant improvement in functional outcomes across nearly all SF-36 subdomains and VAS scores (Table 2). At 1 month postoperatively, Short Form Health Survey physical function (SFPF) improved by 11.2 points in the endoscopic group (p<0.001) compared to 7.0 points in the open group (p=0.005). VAS for leg pain (VASLP) improved by 3.6 in endoscopic cases compared to 3.5 in open cases (both p<0.001). Short Form Health Survey role function emotional improvement was more pronounced in the endoscopic group (8.9 vs. 0.9), though this did not reach statistical significance (p=0.10 in difference-in-difference [DID] analysis). Short Form Health Survey mental health (SFMH) showed early improvement in both groups (5.4 in endoscopic vs. 9.0 in open).

Comparison of mean differences in pre- and postoperative SF-36 scores for patients who underwent endoscopic versus open (microscopic) single-level lumbar spinal decompression

At 3 months, both groups maintained improvements in SFPF, Short Form Health Survey bodily pain (SFBP), and Short Form Health Survey social function (SFSF) scores. By 6 months, VAS for back pain (VASBP) and VASLP reductions were sustained in both cohorts, with more pronounced reduction in back pain among endoscopic patients (-3.30 vs. -3.17), although this difference was not statistically significant (DID=-0.14, p=0.82).

At 2 years, functional scores remained improved in both groups. The SFPF score in the endoscopic group improved by 18.6 points (SD, 21.7; p=0.064), while the open group improved by 36.7 points (SD, 20.9; p=0.007). DID analysis yielded a between-group difference of -18.1 points in SFPF (p=0.155), indicating a trend favoring the open approach for long-term physical functioning, although not statistically significant. In contrast, SFBP, SFSF, and SFMH scores were sustained or modestly improved in both groups, with no statistically significant differences. VAS scores for both back and leg pain remained stable over the 2-year follow-up, indicating durable pain relief across both surgical modalities.

Both endoscopic and open decompression approaches offer durable symptom relief and functional benefit, with minor differences in long-term outcomes that may relate to patient selection, surgical complexity, or learning curve factors.

A formal DID analysis (Table 2) was performed to evaluate whether the magnitude of improvement in functional outcomes differed significantly between surgical techniques. Overall, there was no statistically significant difference in most outcome domains, confirming that both endoscopic and open decompression yield comparable functional recovery. At 6 months, SFPF scores improved more in the open group (DID=-7.37, p=0.23), SFBP showed a trend toward greater improvement in the endoscopic group (DID=7.63, p=0.16).

Although SFPF and SFBP improvements at 2 years were numerically higher in the open group, none of the DID comparisons reached statistical significance. The sustained improvements in VASLP and VASBP were similar in both groups, with DID values showing no significant intergroup disparity.

To explore the impact of surgical experience on functional outcomes, cases were stratified by surgeon and year (Figure 1). Endoscopic SFPF improvements varied across surgeon-year strata, with mean improvements ranging from -7.5 to 35 points. A positive correlation was observed between cumulative case volume and improved mean SFPF scores over time for most surgeons. For example, surgeon 5 in 2023 and 2024 recorded both the highest case volume and the greatest functional gains (SFPF, 35 points). Conversely, earlier years and lower-volume surgeons showed more modest gains or even negative improvement trends.

Figure 1.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey bodily pain (SFBP) score improvement for each surgeon from 2021 to 2024.

This pattern suggests a learning curve effect in endoscopic decompression, with functional outcomes improving as surgeon experience and procedural frequency increased.

The mean duration of operations varied across the years by surgeons. For endoscopic cases, most surgeons had an increase in the mean improvement in SF-36 scores from 2021 to 2024 (Figure 1). For open microscopic cases, most surgeons demonstrated a similar improvement in SF-36 scores across time (Figure 2).

Figure 2.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey social function (SFSF) score improvement for each surgeon from 2021 to 2024.

DISCUSSION

ESS offers several advantages compared to open microscopic surgery, including minimal invasiveness, adaptability in surgical approach selection (such as interlaminar or transforaminal access), the ability to tailor the extent and direction of decompression to patient-specific anatomy using angled optics, a wider endoscopic field of view, and reduced soft tissue damage. These characteristics theoretically translate into faster recovery, less postoperative pain, and shorter hospital stays [31-35]. However, when assessing functional outcomes, both endoscopic and open microscopic decompression surgeries demonstrate similarly significant improvements [36].

This similarity is largely because both surgical techniques share the same principal goal: effective neural decompression. Whether achieved through open microscopic techniques or full endoscopy, symptom relief depends more on the adequacy of decompression rather than the surgical access route. Our findings, consistent with prior studies [37-41], show no significant difference in postoperative SF-36 and VAS scores between groups, reinforcing that the effectiveness of decompression, not the specific technique, drives functional recovery. Similar to a study that demonstrated significant improvement in postoperative functional outcome indicators (VAS and Oswestry Disability Index scores) at 1 year [42], our findings show that patients who underwent ESS for lumbar stenosis demonstrated favorable outcome improvements (SF-36 and VAS), comparable to open microscopic cases.

One study found that the reoperation rate was higher in endoscopic compared to open surgery, although the difference was not statistically significant [33]. In comparison, our study found that reoperation rates were low and similar in both groups.

Moreover, both endoscopic and open microscopic techniques enable targeted decompression of critical anatomic zones, including the central canal, lateral recess, and foramina. Advances in endoscopic instrumentation has allowed the endoscopic technique to replicate the decompressive goals traditionally achieved with open microscopic surgery.

1. Temporal Trends in Endoscopic Versus Microscopic Lumbar Decompression

We observed an increase in the adoption of ESS during the study period, from 40.2% in 2022 to 93.1% in 2024. This trend likely reflects a combination of factors such as growing surgeon familiarity and preference, rapid technological advances in endoscopic systems, and increasing patient demand for minimally invasive treatments.

Among all 8 surgeons, the proportion of ESS cases became greater than open microscopic cases. This is due to ESS being more ergonomically efficient for both the main surgeon and the surgical team, faster operative time, and shorter hospital stays. Efficient decompression can be achieved with minimal soft tissue damage, reducing the length of hospital stay and recovery time.

2. Operative Time: Learning Curve and Experience

One finding in our study was the initially long mean operative time observed in endoscopic surgeries, particularly during the earlier phases of adoption. In 2022, the mean operative duration for endoscopic decompression was 249 minutes, compared to 150 minutes for open microscopic procedures. This difference was largely attributed to the steep learning curve associated with mastering endoscopic techniques, including the intricacies of equipment setup, navigation under a different optical system, and handling intraoperative challenges through limited working channels.

However, as surgeons gained more experience, operative times for endoscopic cases significantly decreased, reaching a mean of 145 minutes by 2024. The surgical cutting time is likely to be much shorter than 145 minutes, as the time recorded reflects the time needed for general anesthesia, positioning and draping the patient.

We examined the relationship between surgeon experience over time and patient outcomes, focusing on caseload and mean duration of operative time and the magnitude of functional score improvement across 4 SF-36 domains and VAS (Figures 16). The analysis was done for all cases (endoscopic and open microscopic) for each surgeon. In the SFPF domain, magnitude of score improvements were generally consistent over time. The SFBP domain showed variable outcomes. Most surgeons had a consistent magnitude of SFBP score improvements, while the others demonstrated a decrease. The Short Form Health Survey general health domain showed stable and small increases in the magnitude of score improvements across the years. For the SFSF, SFRPF, VASLP, and VASBP domains, most surgeons had an increase in magnitude of score improvement over time.

Figure 3.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey general health (SFGH) score improvement for each surgeon from 2021 to 2024.

Figure 4.

Mean operation duration for endoscopic spine surgery and mean Short form role function emotional (SFRPF) score improvement for each surgeon from 2021 to 2024.

Figure 5.

Mean operation duration for endoscopic spine surgery and mean visual analogue scale for back pain (VASBP) score improvement for each surgeon from 2021 to 2024.

Figure 6.

Mean operation duration for endoscopic spine surgery and mean visual analogue scale for leg pain (VASLP) score improvement for each surgeon from 2021 to 2024.

Improved familiarity with instrumentation, better preoperative planning, and refined surgical workflows contributed to faster operative times. Hence, structured training programs and mentorship during the adoption of new surgical technologies is important.

It is expected that as endoscopic techniques become more mainstream, operative times will continue to converge with, or even surpass, those of conventional open microscopic surgeries in efficiency.

3. Recurrence and Reoperation Rates

Both groups showed low recurrence and reoperation rates, underscoring the effectiveness and durability of decompression for both techniques. However, recurrence may become more evident with longer follow-up, and future studies are warranted.

4. Strengths and Limitations

This study has several limitations that should be acknowledged. First, its retrospective design inherently introduces heterogeneity and selection bias. The choice between ESS and open microscopic decompression was non-randomized and guided by surgeon judgment, patient anatomy, radiological characteristics, and evolving surgeon experience. Although we restricted the cohort to elective single-level decompression cases and used DID and temporal trend analyses to mitigate confounding, residual selection bias cannot be fully eliminated. In addition, the exact surgical cutting times were also not consistently recorded, and hence the duration used to calculate the mean operative time, which includes draping and placing the patient under anesthesia, is longer than expected based on current literature. Furthermore, other outcomes such as serum creatinine kinase as a muscle inflammatory marker, estimated blood loss and return to work were not recorded, thus limiting the objective assessment of functional recovery in patients. Another key limitation of this study is that ESS was analyzed as a single category despite encompassing technically distinct procedures, including interlaminar and transforaminal approaches. Differences in approach selection, decompression trajectory, and anatomical targets may influence operative complexity, learning curves, and outcomes. These technique-specific differences could not be fully accounted for due to sample size constraints within each subgroup. A further limitation of this study is the substantial loss to follow-up, with outcome data available for approximately half of the cohort at 2 years. This degree of attrition may introduce survivorship bias and limits the strength of conclusions regarding long-term durability of outcomes. Loss to follow-up was primarily related to missed outpatient appointments and inability to re-establish contact in this retrospective dataset, rather than documented adverse outcomes. To address this, long-term results were interpreted with caution and considered alongside short- and midterm outcomes, where data completeness was higher and consistent improvements were observed across both surgical groups. Future multicenter studies with larger sample sizes, prospective designs, predefined follow-up schedules and randomized or propensity-matched cohorts are needed to better control for selection bias and confounding variables. Such studies would provide more robust evidence regarding the comparative efficacy, safety, and learning curve characteristics of ESS versus open microscopic decompression for LSS.

CONCLUSION

Lumbar ESS is a safe and effective minimally invasive alternative for selected patients with spinal stenosis. When performed by experienced surgeons, it offers comparable functional outcomes to open microscopic decompression, with additional benefits of reduced soft tissue trauma and potentially faster recovery. Recognition of the initial learning curve is important in setting expectations during the early phase of adoption. Personalized surgical planning remains essential to optimize outcomes. Future prospective randomized studies with longer follow-up will be critical to fully validate these findings and further define the role of endoscopic surgery in spinal decompression.

Notes

Conflicts of interest

The authors have nothing to disclose.

Funding/Support

This study received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

Acknowledgments

This study was orally presented at the Singapore Spine Society in March 2025 and at the Global Spine Congress in Istanbul in May 2026.

References

1. Parker SL, Godil SS, Mendenhall SK, Zuckerman SL, Shau DN, McGirt MJ. Two-year comprehensive medical management of degenerative lumbar spine disease (lumbar spondylolisthesis, stenosis, or disc herniation): a value analysis of cost, pain, disability, and quality of life: clinical article. J Neurosurg Spine 2014;21:143–9. 10.3171/2014.3.spine1320. 24785973.
2. Abbas J, Peled N, Hershkovitz I, Hamoud K. Facet tropism and orientation: risk factors for degenerative lumbar spinal stenosis. Biomed Res Int 2020;2020:2453503. 10.1155/2020/2453503. 32685454.
3. Kalff R, Ewald C, Waschke A, Gobisch L, Hopf C. Degenerative lumbar spinal stenosis in older people: current treatment options. Dtsch Arztebl Int 2013;110:613–23; quiz 624. 10.3238/arztebl.2013.0613. 24078855.
4. Katz JN, Zimmerman ZE, Mass H, Makhni MC. Diagnosis and management of lumbar spinal stenosis: a review. JAMA 2022;327:1688–99. 10.1001/jama.2022.5921. 35503342.
5. Ravindra VM, Senglaub SS, Rattani A, Dewan MC, Härtl R, Bisson E, et al. Degenerative lumbar spine disease: estimating global incidence and worldwide volume. Global Spine J 2018;8:784–94. 10.1177/2192568218770769. 30560029.
6. Deyo RA, Mirza SK, Martin BI, Kreuter W, Goodman DC, Jarvik JG. Trends, major medical complications, and charges associated with surgery for lumbar spinal stenosis in older adults. JAMA 2010;303:1259–65. 10.1001/jama.2010.338. 20371784.
7. Chang D, Lui A, Matsoyan A, Safaee MM, Aryan H, Ames C. Comparative review of the socioeconomic burden of lower back pain in the united states and globally. Neurospine 2024;21:487–501. 10.14245/ns.2448372.186. 38955526.
8. Chen S, Chen M, Wu X, Lin S, Tao C, Cao H, et al. Global, regional and national burden of low back pain 1990-2019: A systematic analysis of the Global Burden of Disease study 2019. J Orthop Translat 2022;32:49–58. 10.1016/j.jot.2021.07.005. 34934626.
9. Zheng C, Huang H, Zhang L, Wang Y, Li J, Guo Y, et al. The burden of low back pain and predictions in Asia-Pacific region, 1990-2021: a comparative analysis of China, Japan, Thailand, and Pakistan. Front Med (Lausanne) 2026;13:1693067. 10.3389/fmed.2026.1693067. 41716806.
10. Overview of the HCUP Nationwide Inpatient Sample (NIS). Healthcare cost and utilization project — HCUP. A federal-state-industry partnership in health data [Internet]. Rockville (MD): Agency for Healthcare Research and Quality; 2001. [cited 2026 Jan 7]. Available from: https://hcup-us.ahrq.gov/db/nation/nis/Overview_of_NIS_2001.pdf.
11. Kang DH, Lee S, Kim HJ, Park SM, Yeom JS. Probability for surgical treatment in patients with lumbar spinal stenosis according to the stenotic lesion severity: a 5-10-year follow-up study. BMC Musculoskelet Disord 2022;23:573. 10.1186/s12891-022-05510-7.
12. Davison MA, Lilly DT, Moreno J, Bagley C, Adogwa O. A comparison of successful versus failed nonoperative treatment approaches in patients with degenerative conditions of the lumbar spine. J Clin Neurosci 2021;86:71–8. 10.1016/j.jocn.2020.12.033.
13. Adogwa O, Davison MA, Vuong VD, Khalid S, Lilly DT, Desai SA, et al. Long-term costs of maximum nonoperative treatments in patients with symptomatic lumbar stenosis or spondylolisthesis that ultimately required surgery: a 5-year cost analysis. Spine (Phila Pa 1976) 2019;44:424–30. 10.1097/BRS.0000000000002849. 30130337.
14. Weinstein JN, Tosteson TD, Lurie JD, Tosteson AN, Blood E, Hanscom B, et al. Surgical versus nonsurgical therapy for lumbar spinal stenosis. N Engl J Med 2008;358:794–810. 10.1056/nejmoa0707136. 18287602.
15. Amundsen T, Weber H, Nordal HJ, Magnaes B, Abdelnoor M, Lilleâs F. Lumbar spinal stenosis: conservative or surgical management?: A prospective 10-year study. Spine (Phila Pa 1976) 2000;25:1424–35; discussion 1435-36. 10.1097/00007632-200006010-00016. 10828926.
16. Yang Z, Wang H, Li W, Hu W. Comparative effects and safety of full-endoscopic versus microscopic spinal decompression for lumbar spinal stenosis: a meta-analysis and statistical power analysis of 6 randomized controlled trials. Neurospine 2022;19:996–1005. 10.14245/ns.2244600.300. 36597637.
17. Eun J, Oh Y. Full-endoscopic spinal surgery for older patients with degenerative spinal pathology: a narrative review. J Minim Invasive Spine Surg Tech 2024;9(Suppl 2):S160–71. 10.21182/jmisst.2024.01256.
18. Duong TV, Tuan PA, Linh PQ, Bao LT, Vu HV, Lam CV, et al. Preliminary outcomes of patients with lumbar disc herniation undergoing unilateral biportal endoscopic spine surgery: a single-center retrospective study in Vietnam. J Minim Invasive Spine Surg Tech 2024;9:84–93. 10.21182/jmisst.2023.01046.
19. Liang J, Lian L, Liang S, Zhao H, Shu G, Chao J, et al. Efficacy and complications of unilateral biportal endoscopic spinal surgery for lumbar spinal stenosis: a meta-analysis and systematic review. World Neurosurg 2022;159:e91–102. 10.1016/j.wneu.2021.12.005. 34890849.
20. Pairuchvej S, Muljadi JA, Ho JC, Arirachakaran A, Kongtharvonskul J. Full-endoscopic (bi-portal or uni-portal) versus microscopic lumbar decompression laminectomy in patients with spinal stenosis: systematic review and meta-analysis. Eur J Orthop Surg Traumatol 2020;30:595–611. 10.1007/s00590-019-02604-2. 31863273.
21. Perez-Roman RJ, Gaztanaga W, Lu VM, Wang MY. Endoscopic decompression for the treatment of lumbar spinal stenosis: an updated systematic review and meta-analysis. J Neurosurg Spine 2022;36:549–57. 10.3171/2021.8.spine21890. 34767533.
22. Aygun H, Abdulshafi K. Unilateral biportal endoscopy versus tubular microendoscopy in management of single level degenerative lumbar canal stenosis: a prospective study. Clin Spine Surg 2021;34:E323–8. 10.1097/BSD.0000000000001122. 33470660.
23. Kang T, Park SY, Kang CH, Lee SH, Park JH, Suh SW. Is biportal technique/endoscopic spinal surgery satisfactory for lumbar spinal stenosis patients?: A prospective randomized comparative study. Medicine (Baltimore) 2019;98e15451. 10.1097/MD.0000000000015451. 31045817.
24. Komp M, Hahn P, Oezdemir S, Giannakopoulos A, Heikenfeld R, Kasch R, et al. Bilateral spinal decompression of lumbar central stenosis with the full-endoscopic interlaminar versus microsurgical laminotomy technique: a prospective, randomized, controlled study. Pain Physician 2015;18:61–70. 10.36076/ppj/2015.18.61. 25675060.
25. Park SM, Park J, Jang HS, Heo YW, Han H, Kim HJ, et al. Biportal endoscopic versus microscopic lumbar decompressive laminectomy in patients with spinal stenosis: a randomized controlled trial. Spine J 2020;20:156–65. 10.1016/j.spinee.2019.09.015.
26. Mobbs RJ, Li J, Sivabalan P, Raley D, Rao PJ. Outcomes after decompressive laminectomy for lumbar spinal stenosis: comparison between minimally invasive unilateral laminectomy for bilateral decompression and open laminectomy: clinical article. J Neurosurg Spine 2014;21:179–86. 10.3171/2014.4.SPINE13420. 24878273.
27. Khalid SI, Deysher D, Abou-Mrad T, Wang R, Banoub M, Jiang S, et al. Outcomes following endoscopic versus open single-level lumbar discectomy. J Minim Invasive Spine Surg Tech 2025;10:191–7. 10.21182/jmisst.2025.02236.
28. Arai Y, Hirai T, Yoshii T, Sakai K, Kato T, Enomoto M, et al. A prospective comparative study of 2 minimally invasive decompression procedures for lumbar spinal canal stenosis: unilateral laminotomy for bilateral decompression (ULBD) versus muscle-preserving interlaminar decompression (MILD). Spine (Phila Pa 1976) 2014;39:332–40. 10.1097/BRS.0000000000000136. 24299721.
29. Min WK, Kim JE, Choi DJ, Park EJ, Heo J. Clinical and radiological outcomes between biportal endoscopic decompression and microscopic decompression in lumbar spinal stenosis. J Orthop Sci 2020;25:371–8. 10.1016/j.jos.2019.05.022. 31255456.
30. Cuschieri S. The STROBE guidelines. Saudi J Anaesth 2019;13(Suppl 1):S31–4. 10.4103/sja.sja_543_18. 30930717.
31. Choi WS KJ, Hur JW, Song JH, Kim KT. Endoscopic spinal surgery for lumbar spinal stenosis: a systematic review and meta-analysis. Eur Spine J 2019;28:2522–32.
32. Kim JY, Kim HS, Jeon JB, Lee JH, Park JH, Jang IT. The novel technique of uniportal endoscopic interlaminar contralateral approach for coexisting L5-S1 lateral recess, foraminal, and extraforaminal stenosis and its clinical outcomes. J Clin Med 2021;10:1364. 10.3390/jcm10071364. 33810404.
33. Youn MS, Shin JK, Goh TS, Lee JS. Predictors of clinical outcome after endoscopic partial facetectomy for degenerative lumbar foraminal stenosis. World Neurosurg 2019;126:e1482–8. 10.1016/j.wneu.2019.03.126. 30905646.
34. Kim JE, Choi DJ. Biportal endoscopic transforaminal lumbar interbody fusion with arthroscopy. Clin Orthop Surg 2018;10:248–52. 10.4055/cios.2018.10.2.248. 29854350.
35. Tang K, Goldman S, Avrumova F, Lebl DR. Background, techniques, applications, current trends, and future directions of minimally invasive endoscopic spine surgery: a review of literature. World J Orthop 2023;14:197–206. 10.5312/wjo.v14.i4.197. 37155511.
36. Chen T, Zhou G, Chen Z, Yao X, Liu D. Biportal endoscopic decompression vs. microscopic decompression for lumbar canal stenosis: a systematic review and meta-analysis. Exp Ther Med 2020;20:2743–51. 10.3892/etm.2020.9001. 32765769.
37. Gadjradj PS, Harhangi BS, Amelink J, van Susante J, Kamper S, van Tulder M, et al. Percutaneous transforaminal endoscopic discectomy versus open microdiscectomy for lumbar disc herniation: a systematic review and meta-analysis. Spine (Phila Pa 1976) 2021;46:538–49. 10.1097/BRS.0000000000003843. 33290374.
38. Qin R, Liu B, Hao J, Zhou P, Yao Y, Zhang F, et al. Percutaneous endoscopic lumbar discectomy versus posterior open lumbar microdiscectomy for the treatment of symptomatic lumbar disc herniation: a systemic review and meta-analysis. World Neurosurg 2018;120:352–62. 10.1016/j.wneu.2018.08.236. 30205219.
39. Zhang B, Liu S, Liu J, Yu B, Guo W, Li Y, et al. Transforaminal endoscopic discectomy versus conventional microdiscectomy for lumbar discherniation: a systematic review and meta-analysis. J Orthop Surg Res 2018;13:169. 10.1186/s13018-018-0868-0. 29976224.
40. Barber SM, Nakhla J, Konakondla S, Fridley JS, Oyelese AA, Gokaslan ZL, et al. Outcomes of endoscopic discectomy compared with open microdiscectomy and tubular microdiscectomy for lumbar disc herniations: a meta-analysis. J Neurosurg Spine 2019;31:802–15. 10.3171/2019.6.spine19532. 31491760.
41. Lee CH, Choi M, Ryu DS, Choi I, Kim CH, Kim HS, et al. Efficacy and safety of full-endoscopic decompression via interlaminar approach for central or lateral recess spinal stenosis of the lumbar spine: a meta-analysis. Spine (Phila Pa 1976) 2018;43:1756–64. 10.1097/BRS.0000000000002708. 29794584.
42. Liu Y, Van Isseldyk F, Kotheeranurak V, Quillo-Olvera J, Bae J, Choi KC, et al. Transforaminal endoscopic decompression for foraminal stenosis: single-arm meta-analysis and systematic review. World Neurosurg 2022;168:381–91. 10.1016/j.wneu.2022.04.087. 36527217.

Article information Continued

Figure 1.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey bodily pain (SFBP) score improvement for each surgeon from 2021 to 2024.

Figure 2.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey social function (SFSF) score improvement for each surgeon from 2021 to 2024.

Figure 3.

Mean operation duration for endoscopic spine surgery and mean Short Form Health Survey general health (SFGH) score improvement for each surgeon from 2021 to 2024.

Figure 4.

Mean operation duration for endoscopic spine surgery and mean Short form role function emotional (SFRPF) score improvement for each surgeon from 2021 to 2024.

Figure 5.

Mean operation duration for endoscopic spine surgery and mean visual analogue scale for back pain (VASBP) score improvement for each surgeon from 2021 to 2024.

Figure 6.

Mean operation duration for endoscopic spine surgery and mean visual analogue scale for leg pain (VASLP) score improvement for each surgeon from 2021 to 2024.

Table 1.

Clinical characteristics, pathology, and surgical characteristics of patients with lumbar spinal stenosis

Characteristic Endoscopic (N=364) Open microscopic (N=224)
Age (yr) 53.1±16.0 57.0±36.9
Sex
 Male 194 (53.3) 122 (54.5)
 Female 170 (46.7) 102 (45.5)
Race
 Chinese 286 (78.6) 175 (78.1)
 Malay 50 (13.7) 24 (10.7)
 Indian 12 (3.3) 14 (6.3)
 Others 16 (4.4) 11 (4.9)
Smoking
 Yes 46 (12.6) 26 (11.6)
 No 318 (87.4) 198 (88.4)
Body mass index (kg/m2) 26.2±11.6 26.3±4.9
Comorbidities
 Yes 150 (41.2) 83 (37.1)
 No 214 (58.8) 141 (62.9)
Anticoagulant use
 Yes 43 (11.8) 24 (10.7)
 No 321 (88.2) 200 (89.3)
Pathology
 Lateral recess stenosis 210 (57.7) 169 (75.4)
 Foraminal stenosis 94 (25.8) 24 (10.7)
 Central stenosis and cord compression 60 (16.5) 31 (13.8)
Single level
 Yes 364 (100) 131 (58.5)
 No 0 (0) 93 (41.5)
Type of surgery
 Elective 329 (90.4) 206 (92.0)
 Nonelective 35 (9.6) 18 (8.0)
Duration of operation (min) 148.0±75.8 186.0±79.4
Revision operations 1 (0.3) 1 (0.4)
Mean duration of hospital stay (day) 1.3±0.5 1.95±2.35

Table 2.

Comparison of mean differences in pre- and postoperative SF-36 scores for patients who underwent endoscopic versus open (microscopic) single-level lumbar spinal decompression

Timepoint & SF-36 Endoscopic
Open
Test used DID DID p-value
Mean±SD p-value Mean±SD p-value
1 Month
 SFPF 11.16±24.56 3.79e-07 6.96±20.42 4.50e-03 T-test 4.199961 0.185974
 SFBP 20.26±21.12 8.17e-17 18.18±22.55 1.38e-09 T-test 2.085194 0.720553
 SFGH 3.88±18.56 7.84e-03 5.92±14.8 6.65e-04 Wilcoxon -2.034861 0.613427
 SFVI 7.07±18.58 1.34e-05 8.72±18.21 1.48e-04 Wilcoxon -1.650999 0.767584
 SFSF 14.4±32.21 8.17e-07 11.66±29.14 1.64e-03 Wilcoxon 2.746769 0.528721
 SFRFE 8.94±35.92 8.09e-03 0.90±23.39 7.54e-01 Wilcoxon 8.035847 0.101822
 SFMH 5.36±19.86 3.10e-05 8.97±17.03 1.86e-05 Wilcoxon -3.610654 0.385395
 VASBP -3.06±2.62 1.18e-27 -2.15±2.93 4.29e-07 Wilcoxon -0.908905 0.028952
 VASLP -3.64±2.66 1.54e-33 -3.50±2.89 4.45e-16 T-test -0.140288 0.729555
3 Months
 SFPF 17.19±25.05 1.31e-09 18.17±21.53 1.64e-08 T-test -0.979167 0.795787
 SFRPF 31.77±41.12 4.28e-09 40.42±40.41 1.63e-07 Wilcoxon -8.645833 0.174447
 SFBP 20.08±23.45 4.48e-13 22.52±21.03 1.74e-11 T-test -2.433333 0.502496
 SFGH 2.06±16.47 1.16e-01 3.27±14.51 8.63e-02 T-test -1.204167 0.910578
 SFVI 7.55±16.94 9.21e-05 10.33±19.26 1.16e-04 Wilcoxon -2.781250 0.289745
 SFSF 18.88±35.26 9.52e-07 17.71±25.86 1.48e-05 Wilcoxon 1.171875 0.701596
 SFMH 7.13±17.64 9.92e-06 8.93±13.65 4.21e-06 T-test -1.808333 0.316242
 VASBP -2.95±2.59 5.73e-19 -2.82±2.34 2.10e-09 Wilcoxon -0.131250 0.635780
 VASLP -3.92±2.68 1.77e-25 -4.12±2.79 1.42e-16 T-test 0.200000 0.659242
6 Months
 SFPF 15.76±25.54 4.41e-06 23.13±25.32 1.72e-04 T-test -7.367424 0.230172
 SFBP 25.92±27.49 1.17e-10 18.29±20.54 2.28e-04 T-test 7.632576 0.162314
 SFGH 2.11±17.08 3.20e-01 0.50±14.83 8.70e-01 T-test 1.606061 0.664977
 SFVI 6.14±20.13 1.59e-02 10.83±18.92 1.01e-02 T-test -4.696970 0.311709
 SFSF 23.67±36.5 4.99e-06 19.79±29.7 3.41e-03 T-test 3.882576 0.576937
 SFRFE 9.60±36.4 4.37e-02 0.00±35.44 1.00e+00 Wilcoxon 9.595960 0.315182
 SFMH 9.39±20.22 4.22e-04 8.33±13.34 5.55e-03 T-test 1.060606 0.926997
 VASBP -3.30±2.97 4.11e-13 -3.17±2.28 6.04e-07 T-test -0.136364 0.818467
 VASLP -3.86±3.35 7.53e-10 -2.75±2.95 1.38e-04 T-test -1.113636 0.143652
2 Years
 SFPF 18.57±21.74 6.45e-02 36.67±20.9 7.73e-03 T-test -18.09524 0.155272
 SFBP 21.29±28.75 9.79e-02 36.67±25.45 1.68e-02 T-test -15.38095 0.328330
 SFGH 1.43±19.54 8.53e-01 -3.00±34.15 8.38e-01 T-test 4.428571 0.786333
 SFVI 7.86±26.44 4.62e-01 17.50±20.68 9.29e-02 T-test -9.642857 0.476499
 SFSF 19.64±33.74 1.74e-01 18.75±36.01 2.58e-01 T-test 0.892857 0.964275
 SFRFE 23.81±41.79 3.71e-01 11.11±34.43 4.65e-01 Wilcoxon 12.69841 0.683322
 SFMH 5.71±27.02 5.96e-01 6.67±18.88 4.27e-01 T-test -0.952381 0.942035
 VASBP -3.86±3.76 3.49e-02 -4.17±2.04 4.11e-03 T-test 0.3100 0.8549
 VASLP -4.43±4.20 3.15e-02 -5.17±2.23 2.36e-03 T-test 0.74 0.6956

SF-36, 36-Item Short Form Health Survey; DID, difference-in-differences; SFPF, Short Form Health Survey physical function; SFBP, Short Form Health Survey bodily pain; SFGH, Short Form Health Survey general health; SFVI, Short Form Health Survey vitality; SFSF, Short Form Health Survey social function; SFRFE, Short Form Health Survey role function emotional; SFMH Short Form Health Survey mental health; VASBP, visual analogue scale for back pain; VASLP, visual analogue scale for leg pain.